Oxford - An eight-week reduction diet with meal replacement products helped motivated obese people in randomized study in the British Medical Journal () to achieve significant weight loss, which was largely retained even after year.
Most diets only have temporary effect. This is especially true for reduction diets that rely on low-calorie meal replacement products. Most participants soon long for the day when they can finally eat their fill again, which usually results in immediate and often excessive weight gain.
It seems diet developed by British biochemists now to achieve lasting effect. The "" relies on meal replacement products, which are the sole source of food for the first 12 weeks. The participants eat 4 formula food products (soups, shakes and bars) and 750 ml of skimmed milk per day. In addition, there are 2.25 liters of water or drinks with little or no energy supply and fiber supplement. The energy intake is only 810 kcal / day (with normal daily requirement of most adults of 2,000 kcal).
This diet was achieved in 138 of 278 participants in the DROPLET study, which was drawn into the "Cambridge Weight Plan" had been weight reduction of 13.3 kg, while the 140 participants in the control group, who were offered weight management by their family doctor, lost as much as 3.3 kg. Before the start of the study, the mean 47-year-old participants weighed an average of 105.2 and 107.9 kg, respectively. At an average of 37, their BMI was in range in which secondary diseases are to be expected: 20% already had type 2 diabetes, 30% arterial hypertension.
After 3 more months, in which the patients attended regular meetings and continued to eat one meal of the day with meal replacement products, the participants were able to the weight reduction even increased to 15.1 kg (compared to decrease of 4.5 kg in the control group).
After that - the meal replacement products had meanwhile been used up - there was continuous increase in weight. At the end of the study after one year, the participants on the radical diet weighed 10.7 kg less than before the start of the study. In the control group, the participants were able to maintain weight loss of 3.1 kg.
The advantage over the control group was 7.2 kg and, with 95% confidence interval, was between 4.9 and 9.4 kg statistically significant.The team led by Susan Jebb from the Nuffield Department of Primary Care Health Sciences at Oxford University therefore speaks of successful outcome of the study: 45% of the participants would have achieved weight loss of 10% or more, compared with only 15% in the control group with weight management to the family doctor, who is usually classified as ineffective (but at least achieved weight reduction of 3.1 kg in the study).
The next few years will show whether the optimism is justified. An extrapolation of the weight curve suggests that the participants will have regained their initial weight after 3 years at the latest.