Munich - The first cluster of 2019-nCoV infections in Germany shows that the virus can also be transmitted by asymptomatic people. According to report in the New England Journal of Medicine (2019;), the patients could still be contagious even after the symptoms have ceased.
Doctors at LMU Munich have provided details on the 1st cluster in Germany. Index patient was Chinese business partner who was in Munich between January 19 and 22. At this point, she was symptom-free, write Camilla Rothe, head of the outpatient department for tropical and travel medicine at the University of Munich Hospital, and employees.
Symptoms only appeared on the return flight. The diagnosis was made on January 26th. She informed the company near Munich on January 27th.
The contact examinations that began on the same day then led to the virus detection in 33-year-old employee. He reported that he had sore throat, chills and myalgia on January 24th. The following day, she had fever of 39.1 degrees and productive cough. By the evening of the next day he began to feel better and went back to work on January 27th.
At the presentation, the patient had no elevated temperature and was doing well, reports Rothe. He reported no previous or chronic illnesses and did not undertake any trips abroad in the 14 days before the symptoms appeared.
Despite the symptoms subsided, the virus detection test in 2 nasopharynx swabs and in one sputum sample was positive. A follow-up examination with quantitative PCR test showed high viral load of 10 to the power of 8 copies per milliliter in the sputum.
On January 28, 2019-nCoV was detected in 3 other employees of the company. Only one of these patients had contact with the index patient. The other two patients only had contact with the 1st patient.
All patients with confirmed 2019-nCoV infection were admitted to department for infectious diseases in Munich for clinical monitoring and isolation. So far, none of the 4 confirmed patients showed signs of serious clinical disease.
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